Enantioseparation of organic acids of pharmaceutical interest using eremomycin as a chiral selector.

@article{Prokhorova2011EnantioseparationOO,
  title={Enantioseparation of organic acids of pharmaceutical interest using eremomycin as a chiral selector.},
  author={Aleksandra F Prokhorova and Vladimir A Larin and Anna N Mikhalyuk and Sergei M Staroverov and Elena N Shapovalova and Oleg A Shpigun},
  journal={Electrophoresis},
  year={2011},
  volume={32 19},
  pages={2663-8}
}
Strong adsorption of eremomycin on the fused-silica capillary wall was used for separation of enantiomers by CE. The capillary with adsorbed chiral selector was shown to be easily prepared and has reproducible properties. The effect of the chiral selector concentration, pH and composition of the BGE, and applied voltage on enantioseparation of acidic compounds, such as profens and aromatic carboxylic acids, was investigated. Two native α-amino acids, aspartic acid and glutamic acid, were… CONTINUE READING