Enantioselective transfer aminoallylation: synthesis of optically active homoallylic primary amines.

@article{Sugiura2006EnantioselectiveTA,
  title={Enantioselective transfer aminoallylation: synthesis of optically active homoallylic primary amines.},
  author={Masaharu Sugiura and Chieko Mori and Shū Kobayashi},
  journal={Journal of the American Chemical Society},
  year={2006},
  volume={128 34},
  pages={11038-9}
}
A camphorquinone-derived chiral homoallylic amine was found to react with various aldehydes via imine formation and asymmetric 2-azonia-Cope rearrangement to give optically active homoallylic primary amines. A practical level of enantioselectivity with high functional group tolerance has been attained in this transformation.