Enantioselective reduction of γ-hydroperoxy-α,β-unsaturated carbonyl compounds catalyzed by lipid-coated peroxidase in organic solvents

  title={Enantioselective reduction of $\gamma$-hydroperoxy-$\alpha$,$\beta$-unsaturated carbonyl compounds catalyzed by lipid-coated peroxidase in organic solvents},
  author={Hidetaka Nagatomo and Yoh-ichi Matsushita and Kazuhiro Sugamoto and Takanao Matsui},
Abstract The reduction of racemic γ-hydroperoxy-α,β-unsaturated carbonyl compounds in the presence of lipid-coated horseradish peroxidase as a homogenious catalyst in organic solvents such as toluene, benzene and chlororform containing a small amount of water enantioselectively afforded optical active (R)-alcohols and (S)-hydroperoxides, respectively. 
3 Citations
Enantioselective Reduction of γ-Hydroperoxy-α,β-unsaturated Carbonyl Compounds Catalyzed by Lipid-Coated Peroxidase in Organic Solvents.
Abstract The reduction of racemic γ-hydroperoxy-α,β-unsaturated carbonyl compounds in the presence of lipid-coated horseradish peroxidase as a homogenious catalyst in organic solvents such asExpand
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The kinetic resolution of chiral diastereomeric hydroperoxy homoallylic alcohols 1 by horseradish peroxidase-catalyzed asymmetric reduction affords the optically active (R,R) or (R,S) allylic diols 2Expand
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