Enantioselective Ring Opening of meso-Cyclohexene Epoxide with Phenyllithium Catalyzed by Chiral Schiff Base Ligands

Abstract

A library of chiral Schiff base ligands was synthesized from aromatic aldehydes and chiral amino alcohols. These ligands were then screened as catalysts in the asymmetric ring opening of meso-cyclohexene epoxide with phenyllithium to give (1S,2R)phenylcyclohexanol in 9-67% ee. 

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Cite this paper

@inproceedings{Cortez2004EnantioselectiveRO, title={Enantioselective Ring Opening of meso-Cyclohexene Epoxide with Phenyllithium Catalyzed by Chiral Schiff Base Ligands}, author={Norma Aid{\'e} Cortez and Luc{\'i}a Z. Flores-L{\'o}pez and Miguel Parra-Hake and Gerardo Aguirre and Lars Hellberg and Ratnasamy Somanathan}, year={2004} }