Enantioselective Extraction System Containing Binary Chiral Selectors and Chromatographic Enantioseparation Method for Determination of the Absolute Configuration of Enantiomers of Cyclopentolate

@inproceedings{Szwed2013EnantioselectiveES,
  title={Enantioselective Extraction System Containing Binary Chiral Selectors and Chromatographic Enantioseparation Method for Determination of the Absolute Configuration of Enantiomers of Cyclopentolate},
  author={Kamila Szwed and Marcin G{\'o}recki and Jadwiga Frelek and Monika Asztemborska},
  booktitle={Chromatographia},
  year={2013}
}
The distribution coefficients and enantioseparation of cyclopentolate were studied in an extraction system containing d-tartaric acid ditertbutyl ester in organic phase and 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) in aqueous phase. Various parameters involved in the enantioseparation such as the type and the concentration of chiral selectors, pH value and a wide range of organic solvents were investigated. The maximum enantioselectivity (α = 2.13) and optimum distribution coefficients (KR = 0… CONTINUE READING

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The distribution coefficients and enantioseparation of cyclopentolate were studied in an extraction system containing d - tartaric acid ditertbutyl ester in organic phase and 2-hydroxypropyl-β-cyclodextrin ( HP-β-CD ) in aqueous phase .
The distribution coefficients and enantioseparation of cyclopentolate were studied in an extraction system containing d - tartaric acid ditertbutyl ester in organic phase and 2-hydroxypropyl-β-cyclodextrin ( HP-β-CD ) in aqueous phase .
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