Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.

@article{Nmeth2011EnantiomericSO,
  title={Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.},
  author={Krisztina N{\'e}meth and G{\'a}bor T{\'a}rk{\'a}nyi and Erzs{\'e}bet Varga and T{\'i}mea Imre and R{\'e}ka Mizsei and R{\'o}bert Iv{\'a}nyi and J{\'u}lia Visy and Julianna Szeman and L{\'a}szl{\'o} Jicsinszky and Lajos Szente and Mikl{\'o}s Simonyi},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2011},
  volume={54 3},
  pages={475-81}
}
Capillary electrophoresis (CE) methods for chiral resolution of five antimalarial drugs (primaquine, tafenoquine, mefloquine, chloroquine and quinacrine) were developed by using a wide selection of neutral and anionic cyclodextrin (CD) derivatives. The use of sulfobutyl-β-CD and carboxymethyl-β-CD (CMBCD) resulted in good resolution of quinacrine and tafenoquine, respectively. New results are presented for resolutions of chloroquine and mefloquine. Application of carboxyalkyl- and sulfobutyl-CD… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Enantiomeric separation of trimetoquinol

  • H. Nishi, K. Nakamura, H. Nakai, T. Sato, S. Terabe
  • denopamine and timepidium by capillary…
  • 1995
Highly Influential
4 Excerpts

Chiral separation of drugs by capillary electrophoresis using beta-cyclodextrin polymer

  • H. Nishi, K. Nakamura, H. Nakai, T. Sato
  • J. Chromatogr. A 678
  • 1994
Highly Influential
4 Excerpts

Chiral separation of drugs using cyclodextrins in capillary zone electrophoresis

  • H. Nishi, Y. Kokusenya, T. Miyamoto, T. Sato
  • J. Chromatogr. A 659
  • 1994
Highly Influential
4 Excerpts

Bonato , Enantioselective analysis of antimalarial drugs and their metabolites

  • P. S. I. R. S. Magalhaes
  • Curr . Pharmaceut . Anal .
  • 2010

Enantioselective analysis of antimalarial drugs and their metabolites

  • I.R.S. Magalhaes, P. S. Bonato
  • Curr. Pharmaceut. Anal. 6
  • 2010
3 Excerpts

Chiral separation basic and zwitterionic drugs by highly sulphated cyclodextrins using shortend injection capillary electrophoresis

  • A. Shafaati M. Zandkarimi, S. M. Foroutan
  • Iranian J . Pharmaceut . Res .
  • 2008

Enantioseparationof someclinicallyuseddrugsbycapillaryelectrophoresis using sulphated cyclodextrin as a chiral selector

  • D. M. Chen, Y. Yang, B. Tang, J. J. Gao, H. Y. Aboul-Enein
  • Chromatographia
  • 2005

Bonato , Enantioselective analysis of primaquine and its metabolite carboxyprimaquineby capillary electrophoresis

  • F. E. Stanley, A. M. Stalcup
  • 2004

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