Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period.

Abstract

Racemic ketorolac clearance (CL) is significantly higher at delivery, but S-ketorolac disposition determines the analgesic effects. The aim of this study was to investigate the effect of pregnancy and postpartum period on enantiomer-specific (S and R) intravenous (IV) ketorolac pharmacokinetics (PKs). Data in women shortly following cesarean delivery (n=39… (More)
DOI: 10.17305/bjbms.2016.1515

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Cite this paper

@article{Kulo2017EnantiomerspecificKP, title={Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period.}, author={Aida Kulo and A. W. Smits and Sanita Male{\vs}ki{\'c} and Marc van de Velde and Kristel van Calsteren and Jan N J M de Hoon and Ren{\'e} Verbesselt and Jan Deprest and Karel Allegaert}, journal={Bosnian journal of basic medical sciences}, year={2017}, volume={17 1}, pages={54-60} }