Enamel matrix derivative exhibits angiogenic effect in vitro and in a murine model.

@article{Yuan2003EnamelMD,
  title={Enamel matrix derivative exhibits angiogenic effect in vitro and in a murine model.},
  author={Kuo Yuan and Chun-Liang Chen and Ming Te Lin},
  journal={Journal of clinical periodontology},
  year={2003},
  volume={30 8},
  pages={
          732-8
        }
}
OBJECTIVES Angiogenesis is one of the most critical events in the wound healing process. Any increase in angiogenesis could result in more rapid and complete healing. A recent study found that enamel matrix derivative (EMD) could accelerate early periodontal wound healing. We wanted to clarify whether EMD caused an angiogenic effect and, thus, possibly enhanced wound healing. METHODS We performed in vitro proliferation and chemotaxis assays on human umbilical vein endothelial cell (HUVEC… CONTINUE READING
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