Enalapril effects on alcohol intake and other consummatory behaviors in alcoholics

@article{Naranjo1991EnalaprilEO,
  title={Enalapril effects on alcohol intake and other consummatory behaviors in alcoholics},
  author={Claudio A. Naranjo and Karen E Kadlec and Pablo Sanhueza and D Woodley-Remus and Edward Sellers},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1991},
  volume={50}
}
Animal studies suggest that angiotensin‐converting enzyme inhibitors decrease alcohol intake. In a double‐blind crossover study 42 normotensive alcoholics (36 men and six women) aged 24 to 65 years, consuming 8.2 ± 2.3 (mean ± SD) standard alcoholic drinks per day, were randomized to enalapril, 10 mg/day (n = 20) or 20 mg/day (n = 22), and placebo for 4 weeks. They monitored their daily alcohol intake and attended biweekly assessments, but no other treatment or advice was given. Compliance and… Expand
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  • D. A. Fitts
  • Medicine, Chemistry
  • Pharmacology Biochemistry and Behavior
  • 1993
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