EnP1, a microsporidian spore wall protein that enables spores to adhere to and infect host cells in vitro.

@article{Southern2007EnP1AM,
  title={EnP1, a microsporidian spore wall protein that enables spores to adhere to and infect host cells in vitro.},
  author={Timothy R Southern and Carrie E. Jolly and Melissa E Lester and James Russell Hayman},
  journal={Eukaryotic cell},
  year={2007},
  volume={6 8},
  pages={1354-62}
}
Microsporidia are spore-forming fungal pathogens that require the intracellular environment of host cells for propagation. We have shown that spores of the genus Encephalitozoon adhere to host cell surface glycosaminoglycans (GAGs) in vitro and that this adherence serves to modulate the infection process. In this study, a spore wall protein (EnP1; Encephalitozoon cuniculi ECU01_0820) from E. cuniculi and Encephalitozoon intestinalis is found to interact with the host cell surface. Analysis of… CONTINUE READING

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