En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B.
Mark D Chappell
C. B. Lee
Samuel J Danishefsky
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[reaction--see text] Efficient and processable syntheses of key building blocks of the antitumor agent 12,13-desoxyepothilone B (dEpoB) by catalytic asymmetric induction are herein described.
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