Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine

@article{Whitehouse1998EmuOA,
  title={Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine},
  author={Michael Whitehouse and A G Turner and C K Davis and Michael S. Roberts},
  journal={InflammoPharmacology},
  year={1998},
  volume={6},
  pages={1-8}
}
AbstractThe ‘oil’ obtained from emu fat can be a very effective inhibitor of chronic inflammation in rats when applied dermally (with a skin penetration enhancer). Assays for this activity using the adjuvant-induced arthritis model have shown:i.Considerable variability in potency of some commercial oil samples;ii.Little or no correlation of activity with colour or linolenic acid (18:3) content of the oil;iii.Relative stability of some active oils (to heat, ageing at room temperature);iv.The… 
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Anti-inflammatory activity of emu oils in rats
TLDR
Four of the preparations of emu oil were found to be active against adjuvant-induced arthritis in rats, and the efficacies of the emu oils acting transdermally are compared with that of orally administered ibuprofen.
Prevention of adjuvant‐induced cachexia in rats by cyclosporin A
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The results are consistent with CS preventing the release of cytokines which have anorectic and catabolic actions (IL‐1, TNF), although there is also the possibility that CS has effects involving endocrine mechanisms.