Corpus ID: 11183276

Empirical estimates suggest most published medical research is true

  title={Empirical estimates suggest most published medical research is true},
  author={L. Jager and J. Leek},
  journal={arXiv: Applications},
  • L. Jager, J. Leek
  • Published 2013
  • Mathematics
  • arXiv: Applications
  • The accuracy of published medical research is critical both for scientists, physicians and patients who rely on these results. But the fundamental belief in the medical literature was called into serious question by a paper suggesting most published medical research is false. Here we adapt estimation methods from the genomics community to the problem of estimating the rate of false positives in the medical literature using reported P-values as the data. We then collect P-values from the… CONTINUE READING
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