Empirical Primaquine Treatment of Avian Babesiosis in Seabirds

@article{ThijlVanstreels2019EmpiricalPT,
  title={Empirical Primaquine Treatment of Avian Babesiosis in Seabirds},
  author={Ralph Eric Thijl Vanstreels and Renata Hurtado and Albert Snyman and David G. Roberts and Nola J. Parsons and Pierre A. Pistorius},
  journal={Journal of Avian Medicine and Surgery},
  year={2019},
  volume={33},
  pages={258 - 264}
}
Abstract: Babesia species are tickborne hemoprotozoans. Although experiments have shown that primaquine is highly effective in the treatment of Babesia species infections in mammals, this drug has not been widely used for the treatment of avian babesiosis. Consequently, the treatment of this disease for avian patients has traditionally relied on an empirically established imidocarb treatment. In this study, the authors examined the efficacy of primaquine as a treatment alternative for avian… 

References

SHOWING 1-10 OF 28 REFERENCES
Health evaluation of African penguins (Spheniscus demersus) in southern Africa
TLDR
It is indicated that African penguins may be exposed to conservation-significant pathogens in the wild and encourage further studies aiming for the direct detection and/or isolation of these microorganisms.
Babesia: a world emerging.
Malaria in penguins – current perceptions
TLDR
An overview of the aetiology, life cycle and epidemiology of avian malaria is provided, and details on the strategies that can be employed for the diagnostic, treatment and prevention of this disease in captive penguins are provided, discussing possible directions for future research.
Evaluation of selected antiprotozoal drugs in the Babesia microti-hamster model
TLDR
Two 8-aminoquinolines produced clearance of patent parasitemia and blood from infected hamsters treated with WR238605 via an intramuscular injection failed to infect naive hamsters on subpassage, thus producing a parasitologic cure.
A taxonomic review of avian piroplasms of the genus Babesia Starcovici, 1893 (Apicomplexa: Piroplasmorida: Babesiidae)
TLDR
Previously regarded piroplasms of the genera Babesiosoma and Haemohormidium are reappraised and their relationship to Babesia and the Aegyptianella-Rickettsia group of organisms discussed.
Therapeutic Management of Babesia shortii Infection in a Peregrine Falcon (Falco peregrinus)
TLDR
Results of hematologic and plasma biochemical analysis values were all within reference ranges and no trace of parasitic forms could be found in the blood films examined, and the parasite was estimated to be Babesia shortii.
Blood parasites of penguins: a critical review
TLDR
A critical and comprehensive assessment of the current knowledge on blood parasites is provided, providing an overview of their biology, host and geographic distribution, epidemiology, pathology and implications for public health and conservation.
Babesia shortti infection in a common kestrel (Falco tinnunculus) in Catalonia (northeastern Spain).
TLDR
The presence of the avian piroplasm Babesia shortti in a common kestrel admitted in a wildlife recovery centre in Catalonia, Spain, was reported and the bird was anaemic, which might have caused death.
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