Empiric treatment of infections in neutropenic patients with cancer.

  title={Empiric treatment of infections in neutropenic patients with cancer.},
  author={Jean A. Klastersky},
  journal={Reviews of infectious diseases},
  volume={5 Suppl 1},
Febrile episodes in neutropenic patients with cancer should be treated empirically with broad-spectrum antibiotics that are bactericidal and potentially synergistic against the presumed pathogens. At present, the combination of carbenicillin or ticarcillin and amikacin seems optimal. In patients whose fever responds to therapy but who remain neutropenic, the initial empiric regimen should be continued as long as neutropenia persists. The risk of superinfection associated with prolonged… CONTINUE READING
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