Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults.

@article{EliakimRaz2012EmpiricAC,
  title={Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults.},
  author={Noa Eliakim-Raz and Eyal Robenshtok and Daphna Shefet and Anat Gafter-Gvili and Liat Vidal and Mical Paul and Leonard Leibovici},
  journal={The Cochrane database of systematic reviews},
  year={2012},
  volume={9},
  pages={CD004418}
}
BACKGROUND Community-acquired pneumonia (CAP) is caused by various pathogens, traditionally divided into 'typical' and 'atypical'. Initial antibiotic treatment of CAP is usually empirical, customarily covering both typical and atypical pathogens. To date, no sufficient evidence exists to support this broad coverage, while limiting coverage is bound to reduce toxicity, resistance and expense. OBJECTIVES The main objective was to estimate the mortality and proportion with treatment failure… CONTINUE READING

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