228 Citations
The Psycho-Neurology of Cross-Species Affective/Social Neuroscience: Understanding Animal Affective States as a Guide to Development of Novel Psychiatric Treatments.
- PsychologyCurrent topics in behavioral neurosciences
- 2017
The genesis of depression is significantly influenced by sustained overactivity of the separation-distress PANIC system reflecting severed social bonds and the excessive "psychological pain" of loneliness, leading to a downward cascade known as psychological despair.
Determination of emotional endophenotypes: a validation of the Affective Neuroscience Personality Scales and further perspectives.
- PsychologyPsychological assessment
- 2012
The study of endophenotypes, notably with configured self-reports, represents a promising research pathway to overcome the limits of a syndromal approach of psychiatric diseases and new validity evidence based on relations to other variables is offered.
Behavioral models in psychopathology: epistemic and semantic considerations
- PsychologyBehavioral and Brain Functions
- 2019
The use of animals in neurosciences has a long history. It is considered indispensable in areas in which “translational” research is deemed invaluable, such as behavioral pharmacology and comparative…
Non-mammalian models in behavioral neuroscience: consequences for biological psychiatry
- Psychology, BiologyFront. Behav. Neurosci.
- 2015
Behavioral neuroscientific experiments in non-mammalian species, including traditional “model organisms” (zebrafish and Drosophila) as well as in other species which can be used as “reference” are reviewed.
Neurologizing the Psychology of Affects: How Appraisal-Based Constructivism and Basic Emotion Theory Can Coexist
- PsychologyPerspectives on psychological science : a journal of the Association for Psychological Science
- 2007
Human emotion researchers should not ignore these systems and simply look at the complex and highly variable culturally molded manifestations of emotions in humans if they wish to determine what kinds of “natural” emotional processes exist within all mammalian brain.
Prefrontal cortex, dopamine, and jealousy endophenotype
- PsychologyCNS Spectrums
- 2012
A core neural network and core cognitive processes at the basis of (delusional) jealousy are proposed, characterizing this symptom as possible endophenotype.
Emotion processing deficits: A liability spectrum providing insight into comorbidity of mental disorders
- PsychologyNeuroscience & Biobehavioral Reviews
- 2015
Conceptual endophenotypes: A strategy to advance the impact of psychoneuroendocrinology in precision medicine
- Psychology, BiologyPsychoneuroendocrinology
- 2018
References
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Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind.
- Biology, PsychologyNeuro endocrinology letters
- 2002
A foundational view that focuses on similarities in brain, behavior, and various basic psychological features across mammalian species is advocated, offering the potential to link the emerging discipline of evolutionary psychology to its parent scientific disciplines such as biochemistry, physiology, molecular genetics, developmental biology and the neuroscientific analysis of animal behavior.
The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model.
- Psychology, BiologyAddiction
- 2002
It is illustrated how a mammalian model of emotion (i.e. rodent ultrasonic vocalizations) may enable scientists to predict drug-related phenomena such as abuse potential, anatomical location of mediating neural substrates, and the psychological impact of withdrawal.
The endophenotype concept in psychiatry: etymology and strategic intentions.
- Psychology, BiologyThe American journal of psychiatry
- 2003
The authors discuss the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics.
An evolutionary theory of schizophrenia: Cortical connectivity, metarepresentation, and the social brain
- Psychology, BiologyBehavioral and Brain Sciences
- 2004
It is argued that changes in genes regulating the timing of neurodevelopment occurred prior to the migration of Homo sapiens out of Africa 100,000–150,000 years ago, giving rise to the schizotypal spectrum.
Genetics of personality: are we making progress?
- PsychologyMolecular psychiatry
- 2003
In this review, past studies, present problems and future directions concerning the study of personality genetics are discussed.
Genetics of personality: are we making progress?
- PsychologyMolecular Psychiatry
- 2003
For centuries, scientists are intrigued by the differences in personality between individuals. As early as in the ancient Greek civilization, people tried to formulate theories to systematize this…
Neurobiology of emotion perception II: implications for major psychiatric disorders
- Psychology, MedicineBiological Psychiatry
- 2003
An Evolutionary Approach to Psychiatry
- PsychologyThe Australian and New Zealand journal of psychiatry
- 2000
It is argued that this approach can be applied to psychiatric behaviour, that behavioural similarities exist between many psychiatric states and normal behaviour in species other than humans and many of these can be understood as adaptive.
The genetic basis for psychiatric illness in man *
- PsychologyThe European journal of neuroscience
- 2002
Techniques that have been used in psychiatric genetics, and how they have advanced the understanding of complex behaviour are discussed.