Emotional Lability, Intrusiveness, and Catastrophic Reactions

  title={Emotional Lability, Intrusiveness, and Catastrophic Reactions},
  author={Martin Haupt},
  journal={International Psychogeriatrics},
  pages={409 - 414}
  • M. Haupt
  • Published 1 May 1997
  • Psychology, Medicine
  • International Psychogeriatrics
Emotional lability, intrusiveness, and catastrophic reactions are some of the noncognitive psychopathologic phenomena seen in patients with Alzheimer's disease. These symptoms occur frequently throughout the disease course and strongly influence the well-being of patients with dementia and their caregivers. 

Agitation, Aggressive Behavior, and Catastrophic Reactions

  • I. Katz
  • Psychology
    International Psychogeriatrics
  • 2000
The feasibility and usefulness of subtyping aggressive and agitated symptoms in patients with dementia according to whether these behaviors occur spontaneously or in response to environmental factors is considered.

Pathological Laughter and Crying

The pathophysiology and various treatment approaches available for pathological laughing and crying are described, with varying levels of treatment success.

Diagnosis and management of pathological laughter and crying.

The clinical presentation, diagnosis, prevalence, and proposed pathophysiological mechanisms of and available treatment options for spells of laughter or crying because of an underlying mania or depression are focused on.

Neuroanatomy of pathological laughing and crying: a report of the American Neuropsychiatric Association Committee on Research.

An in depth analysis of the neuroanatomy of lesions seen in patients with pathological laughing and crying is provided, the relevant functional neuroimaging and electrophysiological stimulation studies in human subjects are discussed, and the current treatment options are summarized.

Review of pseudobulbar affect including a novel and potential therapy.

  • R. SchifferL. Pope
  • Psychology, Medicine
    The Journal of neuropsychiatry and clinical neurosciences
  • 2005
Evidence suggests that treatment with a fixed combination of dextromethorphan and the cytochrome P450 2D6 enzyme inhibitor, quinidine, can improve PBA.

Pseudobulbar affect: an under-recognized and under-treated neurological disorder

The overall prevalence of PBA was estimated to be about 10% across these commonly associated underlying neurological conditions and appears to be under-recognized.

When white collar criminals turn to fatal violence: The impact of narcissism and psychopathy

The present article takes as its point of departure Perri's view, according to whom the impact of personality traits such as psychopathy and narcissism has unduly been omitted in research on white ...

Non-Cognitive Disturbances and Patient Characteristics: Prevalence and Relationship in Alzheimer's Disease

The primary aim of this exploratory study was to determine the spectrum of non-cognitive symptom manifestation in a cohort with Alzheimer's disease. The secondary aim was to explore the relationship

Pseudobulbar affect: prevalence and quality of life impact in movement disorders

A validated self-administered screening instrument, the Center for Neurologic Study-Lability Scale (CNS-LS), was used to study the prevalence of PBA, its association with mood symptoms, and the quality of life impact and found patients with PBA tend to have more depressive symptoms and poorerquality of life.

Pathological Laughing and Crying

SSRIs are recommended as first-line pharmacotherapy for this disorder and other treatment options, including TCAs, noradrenergic reuptake inhibitors, novel antidepressants, dopaminergic agents and uncompetitive NMDA receptor antagonists may be useful second-line treatments.



A rating scale for aggressive behaviour in the elderly – the RAGE

A 21-item rating scale for measuring aggressive behaviour in psychogeriatric in-patients is described and should prove valuable in treatment studies and in studies which aim to investigate the correlates of aggressive behaviour.

The Dementia Signs and Symptoms Scale: A New Scale for Comprehensive Assessment of Psychopathology in Alzheimer's Disease.

  • D. LoreckF. BylsmaM. Folstein
  • Psychology, Medicine
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 1994
The Dementia Signs and Symptoms (DSS) Scale documents non-cognitive signs and symptoms in dementia and correlated with corresponding scale scores, confirming construct validity.

A Metaanalysis of Controlled Trials of Neuroleptic Treatment in Dementia

Clinically, neuroleptics treatment changed the improvement rate in agitated dementia patients from .41 to .59 (binomial effect‐size display), which indicates that 18 of 100 dementia patients benefited from neuroleptic treatment (beyond that of placebo) and is consistent with the modest efficacy described in previous qualitative reviews.

The Behavior Rating Scale for Dementia of the Consortium to Establish a Registry for Alzheimer's Disease. The Behavioral Pathology Committee of the Consortium to Establish a Registry for Alzheimer's Disease.

The Behavior Rating Scale for Dementia provides a standardized, reliable measure that can be administered to caregivers of demented subjects and is available for general use in assessing a wide range of psychopathology in dementia.

The noncognitive symptoms of Alzheimer's disease

  • M. Folstein
  • Psychology
    Journal of the Neurological Sciences
  • 1994

Aggressive behavior in elderly people with dementia : Areview

  • International Journal of Geriatric Psychiatry
  • 1993

Requests for offprints should be directed to Martin Haupt

  • Psychiatrische Klinik der Heinrich-Heine-Universitat, Bergische Landstr

Psychotherapeutic interventions in dementia

  • Dementia

The modification of behavior consequent to cerebral lesions. Psychiatry Quarterly

  • 1936