Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

@article{Hsu2010EmodinIT,
  title={Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.},
  author={Chin-Mu Hsu and Yu-An Hsu and Yuhsin Tsai and F. H. Shieh and Su-Hua Huang and Lei Wan and Fuu-Jen Tsai},
  journal={Biochemical and biophysical research communications},
  year={2010},
  volume={392 4},
  pages={473-8}
}
Emodin--a major component of Rheum palmatum L.-exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. Hepatocellular carcinoma has high-incidence rates and is associated with poor prognosis and high mortality rates. This study was designed to evaluate the effects of emodin on human hepatocarcinoma cell viability and investigate its mechanisms of action in Huh7, Hep3B, and HepG2 cells. To define the molecular changes associated with this process… CONTINUE READING

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