Emodin Regulates Glucose Utilization by Activating AMP-activated Protein Kinase*

  title={Emodin Regulates Glucose Utilization by Activating AMP-activated Protein Kinase*},
  author={Parkyong Song and J. Kim and Jaewang Ghim and J. H. Yoon and Areum Lee and YongHoon Kwon and Hyunjung Hyun and Hyo-youl Moon and H. Choi and P. Berggren and Pann-Ghill Suh and S. Ryu},
  journal={The Journal of Biological Chemistry},
  pages={5732 - 5742}
  • Parkyong Song, J. Kim, +9 authors S. Ryu
  • Published 2013
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • AMP-activated protein kinase has been described as a key signaling protein that can regulate energy homeostasis. [...] Key Result As a result, emodin, a natural anthraquinone derivative, was shown to stimulate AMPK activity in skeletal muscle and liver cells. Emodin enhanced GLUT4 translocation and [(14)C]glucose uptake into the myotube in an AMPK-dependent manner.Expand Abstract
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