Emerging tools to study proteoglycan function during skeletal development.

@article{Brown2016EmergingTT,
  title={Emerging tools to study proteoglycan function during skeletal development.},
  author={Deqing Sun Brown and B. Frank Eames},
  journal={Methods in cell biology},
  year={2016},
  volume={134},
  pages={485-530}
}
In the past 20years, appreciation for the varied roles of proteoglycans (PGs), which are specific types of sugar-coated proteins, has increased dramatically. PGs in the extracellular matrix were long known to impart structural functions to many tissues, especially articular cartilage, which cushions bones and allows mobility at skeletal joints. Indeed… CONTINUE READING