Emerging therapeutic uses of direct‐acting oral anticoagulants: An evidence‐based perspective

  title={Emerging therapeutic uses of direct‐acting oral anticoagulants: An evidence‐based perspective},
  author={E. Raschi and M. Bianchin and R. De Ponti and F. De Ponti and W. Ageno},
  journal={Pharmacological Research},
  • E. Raschi, M. Bianchin, +2 authors W. Ageno
  • Published 2017
  • Medicine
  • Pharmacological Research
  • &NA; Direct‐acting oral anticoagulants (DOACs) were claimed to cause a potential paradigm shift in the therapeutic scenario of patients requiring short‐ and long‐term anticoagulation, by virtue of their pharmacological properties, perceived as innovative. The evidence gathered so far (from pre‐approval pivotal trials to real‐world post‐marketing observational data) consistently confirmed that DOACs are overall comparable to vitamin‐K antagonists (VKAs) in terms of safety, efficacy and… CONTINUE READING
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