Emerging therapeutic targets and agents for glioblastoma migrating cells.

  title={Emerging therapeutic targets and agents for glioblastoma migrating cells.},
  author={Chunhui Di and Austin Mattox and Steve Harward and Cory Adamson},
  journal={Anti-cancer agents in medicinal chemistry},
  volume={10 7},
Glioblastoma multiforme (GBM) is one of the most common and most aggressive types of primary brain tumors in humans. Even with aggressive surgical resections using state of the art preoperative and intraoperative neuroim-aging, along with the most recent techniques in radiotherapy and chemotherapy, the prognosis for GBM patients remains dismal. Survival after diagnosis is about 12-14 months. The tumor cells which already have migrated into normal brain tissue beyond the surgical resection… CONTINUE READING

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