Emerging signaling pathways in hepatocellular carcinoma.

  title={Emerging signaling pathways in hepatocellular carcinoma.},
  author={Agrin Moeini and Helena Cornell{\`a} and Augusto Villanueva},
  journal={Liver cancer},
  volume={1 2},
Signaling pathways have become a major source of targets for novel therapies in hepatocellular carcinoma (HCC). Survival benefits achieved with sorafenib, a multikinase inhibitor, are unprecedented and underscore the importance of improving our understanding of how signaling networks interact in transformed cells. Numerous signaling modules are de-regulated… CONTINUE READING