Emerging roles of regulatory T cells in tumour progression and metastasis

@article{Halvorsen2014EmergingRO,
  title={Emerging roles of regulatory T cells in tumour progression and metastasis},
  author={Elizabeth Christene Halvorsen and Sahar M. A. Mahmoud and Kevin Leslie Bennewith},
  journal={Cancer and Metastasis Reviews},
  year={2014},
  volume={33},
  pages={1025-1041}
}
The metastasis of cancer is a complex and life-threatening process that is only partially understood. Immune suppressive cells are recognized as important contributors to tumour progression and may also promote the development and growth of tumour metastases. Specifically, regulatory T cells (Tregs) have been found to promote primary tumour progression, and emerging pre-clinical data suggests that Tregs may promote metastasis and metastatic tumour growth. While the precise role that Tregs play… CONTINUE READING
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