Emerging roles of p53 and other tumour-suppressor genes in immune regulation

@article{MunozFontela2016EmergingRO,
  title={Emerging roles of p53 and other tumour-suppressor genes in immune regulation},
  author={Cesar Munoz-Fontela and Anna Mandinova and Stuart A. Aaronson and Sam W. Lee},
  journal={Nature Reviews Immunology},
  year={2016},
  volume={16},
  pages={741-750}
}
Tumour-suppressor genes are indispensable for the maintenance of genomic integrity. Recently, several of these genes, including those encoding p53, PTEN, RB1 and ARF, have been implicated in immune responses and inflammatory diseases. In particular, the p53 tumour- suppressor pathway is involved in crucial aspects of tumour immunology and in homeostatic regulation of immune responses. Other studies have identified roles for p53 in various cellular processes, including metabolism and stem cell… CONTINUE READING
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In particular , the p53 tumour- suppressor pathway is involved in crucial aspects of tumour immunology and in homeostatic regulation of immune responses .
In particular , the p53 tumour- suppressor pathway is involved in crucial aspects of tumour immunology and in homeostatic regulation of immune responses .
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