Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells.

@article{Mallanna2010EmergingRO,
  title={Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells.},
  author={Sunil Kumar Mallanna and Angie Rizzino},
  journal={Developmental biology},
  year={2010},
  volume={344 1},
  pages={16-25}
}
MicroRNAs (miRNAs) have emerged as critical regulators of gene expression. These small, non-coding RNAs are believed to regulate more than a third of all protein coding genes, and they have been implicated in the control of virtually all biological processes, including the biology of stem cells. The essential roles of miRNAs in the control of pluripotent stem cells were clearly established by the finding that embryonic stem (ES) cells lacking proteins required for miRNA biogenesis exhibit… CONTINUE READING

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