Emerging roles of microRNAs in chronic pain

  title={Emerging roles of microRNAs in chronic pain},
  author={Atsushi Sakai and Hidenori Suzuki},
  journal={Neurochemistry International},
Chronic pain is a debilitating syndrome caused by a variety of disorders, and represents a major clinical problem because of the lack of adequate medication. In chronic pain, massive changes in gene expression are observed in a variety of cells, including neurons and glia, in the overall somatosensory system from the sensory ganglia to the higher central nervous system. The protein expressions of hundreds of genes are thought to be post-transcriptionally regulated by a single type of microRNA… CONTINUE READING
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