Emerging roles of fibronectin in thrombosis.

  title={Emerging roles of fibronectin in thrombosis.},
  author={Lisa Maurer and Bianca R. Tomasini-Johansson and Deane F Mosher},
  journal={Thrombosis research},
  volume={125 4},
Fibronectin (FN) is a glycoprotein recognized originally in the 1940's as a contaminant of fibrinogen in Cohn fraction I of plasma. Decades of research demonstrated FN synthesis by a variety of cells and defined FN as an essential component of the extracellular matrix with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet thrombus formation and diseases associated with thrombosis including vascular remodeling, atherosclerosis, and… CONTINUE READING

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