Emerging roles of RNA and RNA-binding protein network in cancer cells.

@article{Kim2009EmergingRO,
  title={Emerging roles of RNA and RNA-binding protein network in cancer cells.},
  author={Mee Young Kim and Jung Ho Hur and Sunjoo Jeong},
  journal={BMB reports},
  year={2009},
  volume={42 3},
  pages={125-30}
}
Recent advances in RNA biology reveal unexpected diversity and complexity of cellular RNA metabolism. RNA-binding proteins (RBPs) are essential players in RNA metabolism, regulating RNA splicing, transport, surveillance, decay and translation. Aberrant expression of RBPs affects many steps of RNA metabolism, significantly altering expression of RNA. Thus, altered expression and dysfuncting of RBPs are implicated in the development of various diseases including cancer. In this minireview, we… CONTINUE READING