Emerging roles for modulation of microRNA signatures in cancer chemoprevention.

@article{Neelakandan2012EmergingRF,
  title={Emerging roles for modulation of microRNA signatures in cancer chemoprevention.},
  author={K Neelakandan and Ponnusamy Babu and Sajiv K Nair},
  journal={Current cancer drug targets},
  year={2012},
  volume={12 6},
  pages={716-40}
}
miRNAs are small endogenous non-coding RNAs, approximately 21-nucleotides in length, which are shown to regulate an array of cellular processes such as differentiation, cell cycle, cell proliferation, apoptosis, and angiogenesis which are important in cancer. miRNAs can function as both tumor promoters (oncomiRs) or tumor suppressors by their ability to target numerous biomolecules that are important in carcinogenesis. Aberrant expression of miRNAs is correlated with the development and… CONTINUE READING