Emerging roles for centromeres in meiosis I chromosome segregation

@article{Brar2008EmergingRF,
  title={Emerging roles for centromeres in meiosis I chromosome segregation},
  author={Gloria Ann Brar and Angelika Amon},
  journal={Nature Reviews Genetics},
  year={2008},
  volume={9},
  pages={899-910}
}
Centromeres are an essential and conserved feature of eukaryotic chromosomes, yet recent research indicates that we are just beginning to understand the numerous roles that centromeres have in chromosome segregation. During meiosis I, in particular, centromeres seem to function in many processes in addition to their canonical role in assembling kinetochores, the sites of microtubule attachment. Here we summarize recent advances that place centromeres at the centre of meiosis I, and discuss how… CONTINUE READING

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