Emerging roles for PIWI proteins in cancer.

@article{Tan2015EmergingRF,
  title={Emerging roles for PIWI proteins in cancer.},
  author={Yi Tan and Lianyong Liu and Ming’an Liao and Chaobao Zhang and Shuanggang Hu and M-F Zou and Mingjun Gu and Xiangqi Li},
  journal={Acta biochimica et biophysica Sinica},
  year={2015},
  volume={47 5},
  pages={
          315-24
        }
}
It is generally accepted that PIWI proteins are predominately expressed in the germline but absent in somatic tissues. Their best-characterized role is to suppress transposon expression, which ensures genomic stability in the germline. However, increasing evidence has suggested that PIWI proteins are linked to the hallmarks of cancer defined by Weinberg and Hanahan, such as cell proliferation, anti-apoptosis, genomic instability, invasion and metastasis. This provides new possibilities for… 

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