Emerging role of pannexins in seizures and status epilepticus.

  title={Emerging role of pannexins in seizures and status epilepticus.},
  author={Jaideep Kapur},
  journal={Epilepsy currents},
  volume={12 3},
Commentary Electrical transmission in the central nervous system of invertebrates is maintained by a group of proteins called innexins. By contrast, electrical transmission in vertebrates is carried out by pore-making proteins called connexins. One would assume that the proteins mediating electrical transmission in vertebrates and invertebrates would share sequence homology, but that is not the case. Even though there are structural similarities between connexins and innexins, they show no… CONTINUE READING