Emerging role of adipokines as mediators in atherosclerosis.

  title={Emerging role of adipokines as mediators in atherosclerosis.},
  author={Hanrui Zhang and Jian Cui and Cuihua Zhang},
  journal={World journal of cardiology},
  volume={2 11},
Atherosclerotic cardiovascular disease is a major health problem around the world. Obesity is a primary risk factor for atherosclerosis and is associated with increased morbidity and mortality of cardiovascular diseases. However, the precise molecular pathways underlying this close association remain poorly understood. Adipokines are cytokines, chemokines and hormones secreted by adipose tissue that couple the regulation of lipid accumulation, inflammation, and atherogenesis, and therefore… CONTINUE READING
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