Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems.

@article{Kraft2014EmergingRA,
  title={Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems.},
  author={John C. Kraft and Jennifer P. Freeling and Ziyao Wang and Rodney J. Y. Ho},
  journal={Journal of pharmaceutical sciences},
  year={2014},
  volume={103 1},
  pages={
          29-52
        }
}
Liposomes are spherical-enclosed membrane vesicles mainly constructed with lipids. Lipid nanoparticles are loaded with therapeutics and may not contain an enclosed bilayer. The majority of those clinically approved have diameters of 50-300 nm. The growing interest in nanomedicine has fueled lipid-drug and lipid-protein studies, which provide a foundation for developing lipid particles that improve drug potency and reduce off-target effects. Integrating advances in lipid membrane research has… CONTINUE READING
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