Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression.

@article{DIppolito2012EmergingNR,
  title={Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression.},
  author={Silvia D'Ippolito and Fiorella Di Nicuolo and Riccardo Marana and Roberta Castellani and John T Stinson and Chiara Tersigni and Giovanni Scambia and Nicoletta Di Simone},
  journal={Fertility and sterility},
  year={2012},
  volume={98 4},
  pages={1028-36.e1-2}
}
OBJECTIVE To examine the effects of low molecular weight heparins (LMWHs) on extravillous trophoblast (EVTC) invasiveness and on EVTC expression/secretion of heparin binding-EGF (HB-EGF) and cystein-rich angiogenic inducer 61 (Cyr61), both of which are involved in the process of EVTC invasion. Furthermore, to investigate the intracellular DNA binding activity of activator protein (AP)-1. DESIGN Experimental study. SETTING Department of Obstetrics Gynecology, Università Cattolica del Sacro… CONTINUE READING
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Low-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metalloproteinases and tissue inhibitors

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Effect of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester

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  • Fertil Steril 2012;97:764–70
  • 2012
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Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor–like growth factor expression and promote survival of decidual cells undergoing apoptosis

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  • Fertil Steril 2012;97:169–177.e1
  • 2012
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