Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician.

  title={Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician.},
  author={Shawn Vasoo and Jason N Barreto and Pritish K. Tosh},
  journal={Mayo Clinic proceedings},
  volume={90 3},
The rapid and global spread of antimicrobial-resistant organisms in recent years has been unprecedented. Although resistant gram-positive infections have been concerning to clinicians, the increasing incidence of antibiotic-resistant gram-negative infections has become the most pressing issue in bacterial resistance. Indiscriminate antimicrobial use in humans and animals coupled with increased global connectivity facilitated the transmission of gram-negative infections harboring extended… CONTINUE READING
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