Emerging immunopharmacological targets in multiple sclerosis.

@article{Farjam2015EmergingIT,
  title={Emerging immunopharmacological targets in multiple sclerosis.},
  author={Mojtaba Farjam and Guang-xian Zhang and Bogoljub Ciric and Abdolmohamad M. Rostami},
  journal={Journal of the neurological sciences},
  year={2015},
  volume={358 1-2},
  pages={
          22-30
        }
}
Inflammatory demyelination of the central nervous system (CNS) is the hallmark of multiple sclerosis (MS), a chronic debilitating disease that affects more than 2.5 million individuals worldwide. It has been widely accepted, although not proven, that the major pathogenic mechanism of MS involves myelin-reactive T cell activation in the periphery and migration into the CNS, which subsequently triggers an inflammatory cascade that leads to demyelination and axonal damage. Virtually all MS… CONTINUE READING
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