Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

@inproceedings{Moran2012EmergingFA,
  title={Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs},
  author={Victoria A. Moran and Ranjan J. Perera and Ahmad Mohammad Khalil},
  booktitle={Nucleic acids research},
  year={2012}
}
The recent discovery that the human and other mammalian genomes produce thousands of long non-coding RNAs (lncRNAs) raises many fascinating questions. These mRNA-like molecules, which lack significant protein-coding capacity, have been implicated in a wide range of biological functions through diverse and as yet poorly understood molecular mechanisms. Despite some recent insights into how lncRNAs function in such diverse cellular processes as regulation of gene expression and assembly of… CONTINUE READING

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