Emerging drugs of abuse.

@article{Nelson2014EmergingDO,
  title={Emerging drugs of abuse.},
  author={Michael E. Nelson and Sean M. Bryant and Steven E. Aks},
  journal={Emergency medicine clinics of North America},
  year={2014},
  volume={32 1},
  pages={
          1-28
        }
}
View on PubMed
doi.org
45 Citations
Highly Influential Citations
2
Background Citations
11

Tables from this paper

45 Citations

The ongoing challenge of novel psychoactive drugs of abuse. Part I. Synthetic cannabinoids (IUPAC Technical Report)
Abstract In the past decade, the world has experienced a large increase in the number of novel compounds appearing on the illicit drug market for recreational purposes. Such substances are designed…
Synthetic Cannabinoid Use
TLDR
Early evidence suggests that adverse somatic and psychiatric outcomes associated with the use of SCs may be more prevalent and more severe than those arising from cannabis use.
The Synthetic Cannabinoids Phenomenon.
TLDR
Health professionals should take into account that limited scientific evidence is available regarding the effect of synthetic cannabinoids use in humans and launch more systematic epidemiological studies, to develop and validate screening procedures, and to investigate the neurobiological and psychological correlates and risk factors associated to synthetic cannabinoid use and misuse.
NPS: Medical Consequences Associated with Their Intake.
TLDR
The present chapter aims at providing an overview of the clinical and pharmacological issues relating to these most popular NPS categories, including synthetic cathinones, synthetic cannabinoids, and psychedelics/phenethylamines.
Dark Classics in Chemical Neuroscience: Synthetic Cannabinoids (Spice / K2).
TLDR
Overall, the emergence of synthetic cannabinoids serves as a noteworthy example of the pressing public health challenges associated with the increasing development of easily synthesized, structurally-flexible, highly-potent, psychoactive drugs.
An Update on the Implications of New Psychoactive Substances in Public Health
The emergence of new psychoactive substances has earned a great deal of attention, and several reports of acute poisoning and deaths have been issued involving, for instance, synthetic opiates. In…
Repeated Thrombosis After Synthetic Cannabinoid Use.
New and Emerging Illicit Psychoactive Substances.
Molecular Mechanisms of Action of Novel Psychoactive Substances (NPS). A New Threat for Young Drug Users with Forensic-Toxicological Implications
TLDR
The molecular mechanisms of synthetic opioids, synthetic cannabinoids, stimulants, psychedelics, and hallucinogens were reviewed and mostly involved both a receptor-mediated and non-receptor mediated cellular modulation with multiple neurotransmitters interactions.
Detection of drugs of abuse in urine using the Bruker Toxtyper™: Experiences in a routine clinical laboratory setting
...
...

References

SHOWING 1-10 OF 169 REFERENCES
Alternative Drugs of Abuse
TLDR
This review summarizes the current knowledge of alternative drugs of abuse and highlights their clinical presentations.
Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids
Piperazine compounds as drugs of abuse.
2C or Not 2C: Phenethylamine Designer Drug Review
TLDR
Treatment of 2C intoxication is primarily supportive, but immediate action is required in the context of excited delirium, hyperthermia, and seizure activity.
Spice drugs as a new trend: mode of action, identification and legislation.
Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2
TLDR
The first (to the authors' knowledge) cases of myocardial infarction after smoking K2 are reported, and public education and awareness need to be heightened about the possible health implications of K2.
Synthetic cathinones: chemistry, pharmacology and toxicology of a new class of designer drugs of abuse marketed as "bath salts" or "plant food".
Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market.
Internet Highs—Seizures After Consumption of Synthetic Cannabinoids Purchased Online
TLDR
The authors interpreted the history and findings consistent with the consumption of a large amount of synthetic cannabinoids leading to new-onset seizures and coma as a 48-year-old man who, after consuming the herbal blend, lost consciousness and suffered several episodes of seizures.
Emergency Physicians’ Knowledge of Cannabinoid Designer Drugs
TLDR
Clinically active EPs are unfamiliar with synthetic cannabinoids, and even those who stated they had heard of synthetic cannabinoids answered poorly on basic knowledge questions.
...
...