Emerging concepts in engineering extracellular matrix variants for directing cell phenotype.

@article{Carson2009EmergingCI,
  title={Emerging concepts in engineering extracellular matrix variants for directing cell phenotype.},
  author={Ashley E Carson and Thomas H Barker},
  journal={Regenerative medicine},
  year={2009},
  volume={4 4},
  pages={593-600}
}
Directing specific, complex cell behaviors, such as differentiation, in response to biomaterials for regenerative medicine applications is, at present, a mostly unrealized goal. To date, current technological advances have been inspired by the reductionist point of view, focused on developing simple and merely adequate environments that facilitate simple cellular adhesion. However, even if extracellular matrix (ECM)-derived peptides, such as Arg-Gly-Asp (RGD), have largely demonstrated their… CONTINUE READING

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