Emerging concepts in celiac disease

@article{Treem2004EmergingCI,
  title={Emerging concepts in celiac disease},
  author={William R. Treem},
  journal={Current Opinion in Pediatrics},
  year={2004},
  volume={16},
  pages={552-559}
}
  • W. Treem
  • Published 2004
  • Medicine
  • Current Opinion in Pediatrics
Purpose of review There has been an explosion in knowledge about celiac disease (CD) in the last decade based on the availability of serologic screening tests and the elucidation of some of the important disease susceptibility genes. What has been discovered is that CD is among the most common inherited diseases with a worldwide prevalence of almost 1% of the population. Also, there has been a tremendous expansion of the possible clinical presentations in patients with CD, many of them… Expand
Celiac disease in childhood: evaluation of 140 patients.
TLDR
In order to avoid overlooking CD in patients with extra intestinal symptoms and signs, physicians, especially pediatricians, should be informed about new atypical manifestations of CD. Expand
Celiac disease.
TLDR
The basis of treatment for celiac disease is adherence to a gluten-free diet, which may eliminate symptoms within a few months, and patients should also be evaluated for osteoporosis, thyroid dysfunction, and deficiencies in folic acid, vitamin B12, fat-soluble vitamins, and iron, and treated appropriately. Expand
Prevalence of celiac disease among patients with iron deficiency anemia: personal experience and review of literature.
TLDR
All patients with other wise unexplained IDA should have upper gastrointestinal endoscopy with at least four biopsies from the duodenum to exclude CD, according to the revised Marsh criteria. Expand
The Canadian Celiac Health Survey
TLDR
Improved awareness of celiac disease and greater use of serological screening tests may result in earlier diagnosis and reduced risk of associated conditions. Expand
The Canadian Celiac Health Survey ( Published in Digestive Diseases & Sciences April
Purpose: To characterize the diagnostic process, frequency of associated disorders, family history and impact of a gluten-free diet in individuals with celiac disease. Results: All members of theExpand
Testing strategies and follow-up for coeliac disease in a general internal medicine outpatient department from 2000 to 2005.
TLDR
The number of tests ordered in this institution, more often for abdominal than atypical symptoms, has started to increase in the past two years, and showed that screening tests have found their place in general clinical practice, while the final choice of tests needs to be determined in accordance with available guidelines and local resources. Expand
Infant Feeding Practices and the Risk of Celiac Disease
TLDR
HLA was the strongest risk factor for CDA and Celiac disease and children homozygous for HLADQ2 were at six-fold increased risk of celiac disease compared to those with other risk genotypes, and between-country differences were seen in breastfeeding duration and timing of first introduction to complementary foods. Expand
Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye
TLDR
Current advice is that dietary adherence is necessary to avoid the long-term complications, which are, principally, osteoporosis and small bowel lymphoma, but risk of these complications diminishes very considerably in patients who are on a gluten-free diet. Expand
Coeliac disease in primary care: evaluation of a case-finding strategy.
  • I. Berti, R. Della Vedova, +7 authors A. Ventura
  • Medicine
  • Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2006
TLDR
Case-finding is a feasible and successful strategy for detecting undiagnosed coeliac patients and has the important added value of increasing the awareness of the disease among primary care physicians; it represents a cost-effective alternative to population screening for reducing the burden of undi Diagnosed coeeliac disease. Expand
HLA types in Turkish children with celiac disease.
TLDR
A positive association was found between HLA B13, CW7 and DR17 in Turkish celiac patients in addition to H LA B8, DR7 and DQ2, suggesting that a correlation may exist between genotype and clinical manifestations of CD. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 118 REFERENCES
Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study.
TLDR
The results suggest that CD occurs frequently not only in patients with gastrointestinal symptoms, but also in first- and second-degree relatives and patients with numerous common disorders even in the absence of gastrointestinal symptoms. Expand
Prevalence and clinical characteristics of celiac disease in Downs syndrome in a U.S. study
TLDR
Celiac disease, as diagnosed by positive endomysial antibody tests, has an increased prevalence in children with Downs syndrome in the U.S. as compared with the general population (1/250). Expand
Coeliac disease
TLDR
The Marsh classification of intestinal coeliac lesions, as modified by Oberhuber et al, is used by most pathologists to evaluate the intestinal lesions of patients with CD, both for diagnosis and to assess the regression of the lesions after a gluten free diet. Expand
Changing Presentation of Adult Celiac Disease
TLDR
The percentage of Celiac disease patients presenting with diarrhea has decreased, probably related to the more widespread use of serologic testing for celiac disease. Expand
Risk of malignancy in patients with celiac disease.
TLDR
In this cohort of patients with celiac disease, increased risks of small intestinal adenocarcinoma, esophageal cancer, melanoma, and non-Hodgkin's lymphoma were observed, despite adherence to a gluten-free diet. Expand
Prevalence of Celiac disease among children in Finland.
TLDR
The presence of serum tissue transglutaminase and endomysial autoantibodies is predictive of small-bowel abnormalities indicative of celiac disease and there is a good correlation betweenAutoantibody positivity and specific HLA haplotypes. Expand
The prevalence of celiac disease in at-risk groups of children in the United States.
TLDR
CD is not rare in the United States and may be as common as in Europe, and AGA and EMA are useful for identifying patients who should undergo a small intestinal biopsy. Expand
New developments in childhood Celiac Disease
TLDR
This review addresses new developments in CD with respect to pediatric patients and emphasizes the need for awareness among health-care professionals. Expand
Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001.
TLDR
Milder clinical features and use of serology suggest an increased detection rate, although a true increase in incidence may have also occurred in this well-characterized population. Expand
A prospective study of the incidence of childhood celiac disease.
TLDR
C celiac disease may affect 0.9% of Denver children by 5 years of age, and children positive for the HLA-DR3 allele and females appear to be at increased risk. Expand
...
1
2
3
4
5
...