Emerging concepts in celiac disease

  title={Emerging concepts in celiac disease},
  author={William R. Treem},
  journal={Current Opinion in Pediatrics},
  • W. Treem
  • Published 1 October 2004
  • Medicine
  • Current Opinion in Pediatrics
Purpose of review There has been an explosion in knowledge about celiac disease (CD) in the last decade based on the availability of serologic screening tests and the elucidation of some of the important disease susceptibility genes. What has been discovered is that CD is among the most common inherited diseases with a worldwide prevalence of almost 1% of the population. Also, there has been a tremendous expansion of the possible clinical presentations in patients with CD, many of them… 

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The Marsh classification of intestinal coeliac lesions, as modified by Oberhuber et al, is used by most pathologists to evaluate the intestinal lesions of patients with CD, both for diagnosis and to assess the regression of the lesions after a gluten free diet.

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