Emerging avenues linking inflammation and cancer.

  title={Emerging avenues linking inflammation and cancer.},
  author={Joydeb Kumar Kundu and Y. -J. Surh},
  journal={Free radical biology & medicine},
  volume={52 9},
The role of inflammation in carcinogenesis has been extensively investigated and well documented. Many biochemical processes that are altered during chronic inflammation have been implicated in tumorigenesis. These include shifting cellular redox balance toward oxidative stress; induction of genomic instability; increased DNA damage; stimulation of cell proliferation, metastasis, and angiogenesis; deregulation of cellular epigenetic control of gene expression; and inappropriate epithelial-to… CONTINUE READING