Emerging anti-cancer molecular mechanisms of aminobisphosphonates.

@article{Caraglia2006EmergingAM,
  title={Emerging anti-cancer molecular mechanisms of aminobisphosphonates.},
  author={Michele Caraglia and Donatella Santini and Monica Marra and Bruno Vincenzi and Giuseppe Tonini and Alfredo Budillon},
  journal={Endocrine-related cancer},
  year={2006},
  volume={13 1},
  pages={
          7-26
        }
}
  • Michele Caraglia, Donatella Santini, +3 authors Alfredo Budillon
  • Published in Endocrine-related cancer 2006
  • Biology, Medicine
  • Bone metastases are common in patients with many types of cancer, especially breast and prostate cancer--in which the incidence is approximately 70% among patients with advanced metastatic disease. Aminobisphosphonates (NBPs) have entered clinical practice in the treatment of bone metastases from several neoplasms, including breast and prostate adenocarcinoma, as a result of their anti-resorption properties. However, evidence has accumulated on the direct anti-tumour effects of NBPs. This… CONTINUE READING

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