Emerging Role of Angiotensin Type 2 Receptor (AT2R)/Akt/NO Pathway in Vascular Smooth Muscle Cell in the Hyperthyroidism

Abstract

Hyperthyroidism is characterized by increased vascular relaxation and decreased vascular contraction and is associated with augmented levels of triiodothyronine (T3) that contribute to the diminished systemic vascular resistance found in this condition. T3 leads to augmented NO production via PI3K/Akt signaling pathway, which in turn causes vascular smooth… (More)
DOI: 10.1371/journal.pone.0061982

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Cite this paper

@inproceedings{CarrilloSeplveda2013EmergingRO, title={Emerging Role of Angiotensin Type 2 Receptor (AT2R)/Akt/NO Pathway in Vascular Smooth Muscle Cell in the Hyperthyroidism}, author={Maria Al{\'i}cia Carrillo-Sep{\'u}lveda and Graziela Scalianti Ceravolo and Cristina Ribas Furstenau and Priscilla de Souza Monteiro and Zuleica Bruno-Fortes and Maria Helena Catelli de Carvalho and Francisco R M Laurindo and Rita C A Tostes and Robert Clinton Webb and Maria Luiza Morais Barreto-Chaves}, booktitle={PloS one}, year={2013} }