Emerging Biological Principles of Metastasis

@article{Lambert2017EmergingBP,
  title={Emerging Biological Principles of Metastasis},
  author={Arthur W Lambert and Diwakar R. Pattabiraman and Robert A Weinberg},
  journal={Cell},
  year={2017},
  volume={168},
  pages={670-691}
}
Metastases account for the great majority of cancer-associated deaths, yet this complex process remains the least understood aspect of cancer biology. As the body of research concerning metastasis continues to grow at a rapid rate, the biological programs that underlie the dissemination and metastatic outgrowth of cancer cells are beginning to come into view. In this review we summarize the cellular and molecular mechanisms involved in metastasis, with a focus on carcinomas where the most is… CONTINUE READING

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