Emergent human pathogen simian virus 40 and its role in cancer.

@article{Vilchez2004EmergentHP,
  title={Emergent human pathogen simian virus 40 and its role in cancer.},
  author={Regis A. Vilchez and Janet S Butel},
  journal={Clinical microbiology reviews},
  year={2004},
  volume={17 3},
  pages={495-508, table of contents}
}
The polyomavirus simian virus 40 (SV40) is a known oncogenic DNA virus which induces primary brain and bone cancers, malignant mesothelioma, and lymphomas in laboratory animals. Persuasive evidence now indicates that SV40 is causing infections in humans today and represents an emerging pathogen. A meta-analysis of molecular, pathological, and clinical data from 1,793 cancer patients indicates that there is a significant excess risk of SV40 associated with human primary brain cancers, primary… CONTINUE READING