Emergent dynamics of fast ripples in the epileptic hippocampus.

  title={Emergent dynamics of fast ripples in the epileptic hippocampus.},
  author={Jos{\'e} Manuel Ibarz and Guglielmo Foffani and Elena Cid and Marion Inostroza and Liset Menendez de la Prida},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={30 48},
Fast ripples are a type of transient high-frequency oscillations recorded from the epileptogenic regions of the hippocampus and the temporal cortex of epileptic humans and rodents. These events presumably reflect hypersynchronous bursting of pyramidal cells. However, the oscillatory spectral content of fast ripples varies from 250 to 800 Hz, well above the maximal firing frequency of most hippocampal pyramidal neurons. How such high-frequency oscillations are generated is therefore unclear… CONTINUE READING