Emergent bistability: Effects of additive and multiplicative noise
@article{Ghosh2012EmergentBE, title={Emergent bistability: Effects of additive and multiplicative noise}, author={Sumana Ghosh and S. Banerjee and I Bose}, journal={The European Physical Journal E}, year={2012}, volume={35}, pages={1-14} }
Positive feedback and cooperativity in the regulation of gene expression are generally considered to be necessary for obtaining bistable expression states. Recently, a novel mechanism of bistability termed emergent bistability has been proposed which involves only positive feedback and no cooperativity in the regulation. An additional positive feedback loop is effectively generated due to the inhibition of cellular growth by the synthesized proteins. The mechanism, demonstrated for a synthetic…
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